The smart Trick of ceesdekker That No One is Discussing
The smart Trick of ceesdekker That No One is Discussing
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2009, discovery of a fresh phenotype for microorganisms in slim nanofluidic slits; and 1st detection of area protein buildings together DNA making use of reliable-condition nanopores
But how do morality, the dignity of the individual, my knowledge in the meaning of everyday living, observe through the movement of atoms? A purely naturalistic standpoint fails listed here; a Christian perspective, I feel, is a way more affordable solution to interpret these areas of reality.’
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Because 2000, Dekker has shifted the leading focus of his perform towards biophysics in which he scientific tests the properties of single biomolecules and cells using the instruments of nanotechnology. This change of area was driven by his fascination for that extraordinary functioning of biological molecular constructions, together with via the lengthy-phrase viewpoint a large number of attention-grabbing discoveries may be anticipated In this particular industry.[five] Present-day lines of study in his biophysics group are within the areas of:[6]
This yielded a breakthrough. In only a few months, we ended up capable of evaluate transport as a result of a person one-walled carbon nanotube. Depending on low-temperature experiments by an excellent PhD pupil in my team, Sander Tans (now a valued colleague and professor at Delft University of Technological innovation with an Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with incredibly extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of one wire bridging two electrodes
All parameters were the identical for each panel In this particular online video, aside from the Original placement of the 6hb rod (shown in blue) around the nanopore. Simulations that terminated early on account of translocation on the rod from the pore are marked by a gray qualifications.
Learning DNA loop extrusion by SMC proteins for chromosome architecture with one-molecule assays.
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Bulk-surface area coupling identifies the mechanistic link amongst Min-protein styles in vivo As well as in vitro
Tests pseudotopological and nontopological versions for SMC-pushed DNA loop extrusion versus roadblock-traversal experiments
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By way of example, we consider the nucleopore complicated, a gateway between the mobile https://www.ceesdekker.net nucleus as well as the cytoplasm. This is a very sophisticated technique and thus difficult to review within a mobile, so we use biomimetics. We reconstruct holes and afterwards insert personal elements with the nucleopore sophisticated to check transport through it at The only-molecule level.’
Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)